Building Medical Device Innovations Together
With publications services ranging from strategic planning to technical writing, our team provides a unified approach to generating and disseminating evidence around a technology’s value proposition.
Telos Partners publications services employs a comprehensive methodology to communicate the value of our clients’ technology through scientific, clinical, and economic evidence.
In the strategic planning phase, the technology and current evidence landscape are evaluated in a gap analysis. Recommendations are then provided to address the gaps through specific studies or analyses.
Data are typically derived from past or new clinical studies, registries, administrative (e.g., facility or payer) databases, or literature reviews in the evidence generation phase. Telos supports study design, data collection, and analysis for new clinical studies through its CRO function. Our professional medical writers then collaborate with the associated physicians and scientists to publish the evidence in peer-reviewed journals.
Baranidharan G, Bretherton B, Montgomery C, Titterington J, Crowther T, Vannabouathong C, Inzana JA, Rotte A. Pain Relief and Safety Outcomes with Cervical 10 kHz Spinal Cord Stimulation: Systematic Literature Review and Meta-analysis. Pain Ther. 2021 May 25. doi: 10.1007/s40122-021-00269-6. Epub ahead of print. PMID: 34031856
Zaslav, K.R., Farr, J., Alfred, R. et al. Treatment of Post-Meniscectomy Knee Symptoms with Medial Meniscus Replacement Results in Greater Pain Reduction and Functional Improvement Than Non-Surgical Care. Knee Surg Sports Traumatol Arthrosc (2021). April 2021.
Coric D, Roybal RR, Grubb M, Rossi V, Yu AK, Swink IR, Long J, Cheng BC, Inzana JA. Bidirectional Expandable Technology for Transforaminal or Posterior Lumbar Interbody Fusion: A Retrospective Analysis of Safety and Performance. Int J Spine Surg. Dec. 2020;14(s3):S22-S30.
McKeon BP, Zaslav KR, Alfred RH, et al. Preliminary Results from a US Clinical Trial of a Novel Synthetic Polymer Meniscal Implant. Orthop J Sports Med. Sept. 2020;8(9):2325967120952414.
Ammerman J, Wind J, Goldsmith M, Inzana JA. Lumbar Discectomy and Reoperation Among Workers’ Compensation Cases in Florida and New York: Are Treatment Trends Similar to Other Payer Types? J Occup Environ Med. Sept. 2020; 62(9):478-484.
Golish SR, Groff MW, Araghi A, Inzana JA. Superiority Claims for Spinal Devices: A Systematic Review of Randomized Controlled Trials. Global Spine J. May 2020; 10(3):332-345.
Nagaraja S, Loughran G, Gandhi A, Inzana J, Baumann AP, Kartikeya K, Horner M. Verification, Validation, and Uncertainty Quantification of Spinal Rod Computational Models Under Three-Point Bending. ASME. J. Verif. Valid. Uncert. March 2020; 5(1):011002. doi:10.1115/1.4046329
Krutko AV, Sanginov AJ, Baykov ES. Predictors of Treatment Success Following Limited Discectomy with Annular Closure for Lumbar Disc Herniation. Int J Spine Surg. Feb. 2020;14(1):38-45.
Lorio M, Kim C, Araghi A, Inzana J, Yue J. ISASS Policy Guideline– Surgical Treatment of Lumbar Disc Herniation with Radiculopathy. Int. J Spine Surg. Published online Dec 23, 2019.
Cho PG, Shin DA, Park SH, Ji GY. Efficacy of a Novel Annular Closure Device after Lumbar Discectomy in Korean Patients: a 24-Month Follow-up of a Randomized Controlled Trial. J Korean Neurosurg Soc. Nov. 2019;62(6):691-699.
Goldberg TD, Maltry JA, Ahuja M, Inzana JA. Logistical and Economic Advantages of Sterile-Packed, Single-Use Instruments for Total Knee Arthroplasty. J Arthroplasty. 2019 Sep;34(9):1876-1883.e2. doi: 0.1016/j.arth.2019.03.011. Epub 2019 Apr 25.
Kursumovic A, Muir JM, Ammerman J, Bostelmann R. The Disability Cascade: A Preventable Consequence of the Loss of Disc Height following Lumbar Microdiscectomy. Cureus. 2019 Jul 18;11(7):e5169. doi: 10.7759/cureus.5169. Review.
Ammerman J, Watters WC, Inzana JA, Carragee G, Groff MW. Closing the Treatment Gap for Lumbar Disc Herniation Patients with Large Annular Defects: A Systematic Review of Techniques and Outcomes in this High-risk Population. Cureus. 2019 May 7;11(5):e4613. doi:10.7759/cureus.4613. Review.
Thaci B, McGirt MJ, Ammerman JM, Thomé C, Kim KD, Ament JD. Reduction of direct costs in high-risk lumbar discectomy patients during the 90-day post-operative period through annular closure. Clinicoecon Outcomes Res. 2019 Feb 28;11:191-197. doi: 10.2147/CEOR.S193603.
Ament JD, Thaci B, Yang Z, Kursumovic A, Bostelmann R, Lanman T, Patrick Johnson J, Fröhlich S, Kim KD. Postoperative direct health care costs of lumbar discectomy are reduced with the use of a novel annular closure device in high-risk patients. Spine J. 2019 Jul;19(7):1170-1179. doi: 10.1016/j.spinee.2019.02.010. Epub 2019 Feb 15.
Ament J, Thaci B, Yang Z, Kulubya E, Hsu W, Bouma G, Kim KD. Cost-effectiveness of a Bone-anchored Annular Closure Device Versus Conventional Lumbar Discectomy in Treating Lumbar Disc Herniations. Spine (Phila Pa 1976). 2019 Jan 1;44(1):5-16. doi: 10.1097/BRS.0000000000002746.
Martens F, Lesage G, Muir JM, Stieber JR. Implantation of a bone-anchored annular closure device in conjunction with tubular minimally invasive discectomy for lumbar disc herniation: a retrospective study. BMC Musculoskelet Disord. 2018 Jul 27;19(1):269. doi: 10.1186/s12891-018-2178-4.
Vácz G, Major B, Gaál D, Petrik L, Horváthy DB, Han W, Holczer T, Simon M, Muir JM, Hornyák I, Lacza Z. Hyperacute serum has markedly better regenerative efficacy than platelet-rich plasma in a human bone oxygen-glucose deprivation model. Regen Med. 2018 Jul 1;13(5):531-543. doi: 10.2217/rme-2017-0141. Epub 2018 Aug 22.
Klassen PD, Hsu WK, Martens F, Inzana JA, van den Brink WA, Groff MW, Thomé C. Post-lumbar discectomy reoperations that are associated with poor clinical and socioeconomic outcomes can be reduced through use of a novel annular closure device: results from a 2-year randomized controlled trial. Clinicoecon Outcomes Res. 2018 June 26;10:349-357. doi: 10.2147/CEOR.S164129.
Kuršumović A, Rath SA. Effectiveness of an annular closure device in a “real-world” population: stratification of registry data using screening criteria from a randomized controlled trial. Med Devices (Auckl). 2018 June 7;11:193-200. doi: 10.2147/MDER.S167381.
Martens F, Vajkoczy P, Jadik S, Hegewald A, Stieber J, Hes R. Patients at the Highest Risk for Reherniation Following Lumbar Discectomy in a Multicenter Randomized Controlled Trial. JB JS Open Access. 2018 Apr 16;3(2):e0037. doi: 10.2106/JBJS.OA.17.00037. 2018 June 28.
MacEwan MR, MacEwan S, Wright AP, Kovacs TR, Batts J, Zhang L. Efficacy of a Nanofabricated Electrospun Wound Matrix in Treating Full-thickness Cutaneous Wounds in a Porcine Model. Wounds. 2018 Feb.;30(2):E21-E24.
Kuršumović A, Rath S. Performance of an Annular Closure Device in a ‘Real-World’, Heterogeneous, At-Risk, Lumbar Discectomy Population. Cureus. 2017 Nov. 6;9(11):e1824. doi: 10.7759/cureus.1824.
MacEwan MR, MacEwan S, Kovacs TR, Batts J. What Makes the Optimal Wound Healing
Material? A Review of Current Science and Introduction of a Synthetic Nanofabricated Wound Care Scaffold. Cureus. 2017 Oct. 2;9(10):e1736. doi: 10.7759/cureus.1736. Review.
MacEwan MR, MacEwan S, Wright AP, Kovacs TR, Batts J, Zhang L. Comparison of a Fully Synthetic Electrospun Matrix to a Bi-Layered Xenograft in Healing Full Thickness Cutaneous Wounds in a Porcine Model. Cureus. 2017 Aug. 27;9(8):e1614. doi: 10.7759/cureus.1614.
Telos works with you to clearly understand your business’ goals. We ask “Why” instead of “How.”
Our team identifies service areas where we can partner to create a plan unique to your business.
We’ll work with you through each phase to accomplish the milestones identified in the plan.
Because we see each client as a true partner, we remain ready to help your business scale as new needs arise.